Booster began

Banner Alzheimer’s
Institute and Notions Strength Analysis Pioneer announced that they are
actively enrolling patients in a new study of the investigational drug
Dimebon(TM) for the treatment of Alzheimer’s disease. The chew over will
evaluate the safety and efficacy of Dimebon in patients with Alzheimer’s
disease taken in league with Aricept(R) (donepezil HCI tablets), an
FDA-approved Alzheimer’s treatment.

According to unusual estimates from the Alzheimer’s Association, more than
5 million people in the United States are living with Alzheimer’s disorder,
a gradual, debilitating and deadly neurodegenerative disability that
destroys brain cells and affects areas of the brains involved in memory,
cognition, judgment, lingua franca and behavior. Currently available therapies
for Alzheimer’s treat the symptoms with modest make in most patients; uncharted
therapies are urgently needed.

Results from a one-year haunt of Dimebon in mild-to-moderate
Alzheimer’s disease — showing statistically critical improvements in
remembrance, thinking, function and behavior — were highlighted at the brand-new
2008 Arizona Alzheimer’s Consortium (AAC) Annual Conference, a community
service event. Gonfalon Alzheimer’s Institute and Sun Vigorousness Research
Guild are both members of the Consortium.

“We are encouraged by the results Dimebon has shown in clinical studies
to date and believe it is imperative to fully assess its commitment in the
fight against Alzheimer’s disease,” said Pierre N. Tariot, M.D., vice-president,
Memory Disorders Center, Leading Alzheimer’s Institute. “We are on top of the world to
be participating in this learning.”

“As the baby boomer populace ages, the number of Alzheimer’s transfer
dramatically proliferating. We must find innovative ways to prescribe for this
devastating disease and slow its progression,” said Marwan Sabbagh, M.D.,
founder and director of clinical delving at Trinkets Healthfulness Research
Institute’s Cleo Roberts Center for Clinical Research. “We incite neighbourhood pub
patients and caregivers to learn more respecting possible enrollment in this
study, as clinical research is vitally important to understanding how we
can better treat Alzheimer’s disease.”

About the Study

The multi-form 1/2 study is designed to evaluate the safety,
tolerability and pharmacokinetics(1) of the investigational drug Dimebon in
the treatment of patients with Alzheimer’s disease. Patients grey 50 and
older with a clinical diagnosis of Alzheimer’s condition, taking Aricept notwithstanding
at least 60 days quondam to enrollment, may be suitable to participate in the
study. The trial is sponsored by Medivation, Inc.

Around Dimebon

Dimebon is an investigational therapy in clinical development quest of the
treatment of Alzheimer’s malady. It targets Alzheimer’s disease
differently than currently available therapies. Monogram studies of Dimebon
obtain shown promise and further study is indicated.

About Flag Alzheimer’s Institute

Banner Alzheimer’s Institute is a treatment and research masterfulness
dedicated to helping patients with memory and conclusion problems. It offers
clinical care for patients; provides education, referral and support
services for family and caregivers; and conducts pre-eminent-steal enquiry in
clinical trials, intellectual imaging and genetics studies. The Institute is
ardent to decree productive Alzheimer’s disease-slowing and prevention
treatments in the shortest just the same from time to time possible. Banner Alzheimer’s Set up is
owned and operated by Phoenix-based Banner Trim, a nonprofit
organization.

About Kickshaws Healthfulness Research Institute

For the sake of 21 years, Brown Health Check out Institute has been a leader
nationally and internationally in the achievement to view answers to disorders
of aging including Alzheimer’s malady, Parkinson’s disability, arthritis and
prostate cancer. The institute, together with its Arizona Alzheimer’s
Consortium partners, has been designated by the National Institutes of
Health as bromide of just 31 Alzheimer’s Disease Centers in the nation. The
institute’s Cleo Roberts Center over the extent of Clinical Research takes laboratory
discoveries to clinical trials that foster hope for new treatments. Sun
Fettle Research Establish is connected with the Sun Health non-profit
community healthcare network.

(1) Pharmacokinetics is the process by which a remedy is concentrating, distributed, metabolized and eliminated by the body.

Miscellany Health Inspection League
http://www.shri.org

View drug information on ARICEPT.